Description
Ofev 150mg Capsules contain Nintedanib, a prescription medicine used to treat Idiopathic Pulmonary Fibrosis (IPF) and other progressive interstitial lung diseases. It helps slow the progression of lung scarring and supports better management of chronic lung conditions. Ofev is widely prescribed for patients diagnosed with IPF, chronic fibrosing interstitial lung disease (ILD), and systemic sclerosis-associated ILD.
If you are looking for Ofev 150mg Capsules in Pakistan, this imported medicine is available in a pack of 60 capsules and should be used only under the supervision of a qualified healthcare professional.
Uses of Ofev 150mg Capsules
Ofev 150mg is prescribed for:
- Idiopathic Pulmonary Fibrosis (IPF).
- Progressive chronic fibrosing interstitial lung diseases (ILDs).
- Systemic sclerosis-associated interstitial lung disease (SSc-ILD).
- Progressive lung fibrosis management.
How Ofev 150mg Works
Nintedanib works by targeting pathways involved in lung tissue scarring. It helps reduce the rate of fibrosis progression, which may help preserve lung function in eligible patients.
Product Specifications
- Brand: Ofev
- Generic Name: Nintedanib
- Strength: 150mg
- Dosage Form: Capsules
- Pack Size: 60 Capsules
- Manufacturer: Boehringer Ingelheim
- Treatment Category: Lung Diseases and Pulmonary Fibrosis
- Prescription Required: Yes
Benefits of Ofev 150mg
- Helps slow the progression of Idiopathic Pulmonary Fibrosis.
- Supports patients with progressive interstitial lung diseases.
- Convenient oral capsule formulation.
- Manufactured by Boehringer Ingelheim.
- Used in long-term pulmonary fibrosis treatment plans.
Possible Side Effects
Some patients may experience:
- Diarrhea.
- Nausea.
- Vomiting.
- Abdominal pain.
- Loss of appetite.
- Weight loss.
- Elevated liver enzymes.
- Fatigue.
- High blood pressure.
Consult your healthcare provider if any side effects become severe or persistent.
Precautions
Before taking Ofev 150mg Capsules, inform your doctor if you have:
- Liver disease.
- Bleeding disorders.
- Cardiovascular conditions.
- Recent surgery.
- Pregnancy or breastfeeding concerns.
- Any known allergies to Nintedanib.
Storage Instructions
- Store in a cool and dry place.
- Keep away from heat and direct sunlight.
- Keep out of the reach of children.
Frequently Asked Questions
What is OFEV 150 mg used for?
OFEV 150 mg treats idiopathic pulmonary fibrosis and progressive fibrosing interstitial lung diseases. It slows lung function decline by blocking fibrotic pathways that cause excessive scar tissue formation in lung tissue.
What is the price of OFEV?
OFEV price in Pakistan ranges from Rs. 190,000 to Rs. 280,000 per 60-capsule pack. Prices vary among suppliers based on sourcing, availability, and market conditions affecting imported medications.
How long can you take OFEV for?
OFEV is intended for long-term use as determined by your physician. Clinical studies evaluated treatment periods of at least 52 weeks, with many patients continuing therapy longer based on tolerability.
How much is nintedanib 150 mg?
Nintedanib 150 mg capsules cost between Rs. 190,000 and Rs. 280,000 for 60 capsules in Pakistan. The price reflects import costs, regulatory requirements, and specialized handling needed for this prescription anti-fibrotic medication.
How Does Ofev Capsules Work?
Ofev capsules contain nintedanib, which blocks multiple tyrosine kinase receptors (PDGFR, FGFR, VEGFR). This action prevents excessive collagen production and fibroblast proliferation, thereby slowing the progression of lung fibrosis and preserving function.
Can We Use Other Medicines with Ofev Capsules?
Many medications can be used with Ofev, but some require caution when taken with it. Strong CYP3A4 inhibitors increase Ofev levels, while inducers decrease effectiveness. Always consult your doctor before combining medications.
How does Ofev (Nintedanib) work to slow lung fibrosis?
Nintedanib inhibits key growth factor receptors that drive fibroblast activation and excessive collagen deposition. By blocking these pathways, Ofev reduces the progression of lung scarring and helps maintain respiratory function.
Can Ofev be taken by pregnant women or patients with liver/kidney issues?
Ofev is contraindicated in pregnancy due to the risk of fetal harm. Patients with moderate-to-severe liver impairment should avoid Ofev. Mild liver impairment requires dose reduction and monitoring.
What should I do if I forget a dose of Ofev?
If you miss an Ofev dose, take your next scheduled dose at the regular time. Never take two doses simultaneously to compensate for missed doses, as this increases the risk of side effects.
How to store Ofev capsules properly?
Store Ofev capsules in the original packaging at room temperature, away from moisture and direct sunlight. Keep away from children and pets. Do not use capsules past the expiration date printed on the packaging.
