Description
Xolair 150mg Injection (Omalizumab)
If your asthma or chronic hives refuse to respond to regular treatment, Xolair 150mg injection offers a targeted option built around one goal: reducing the allergic response that causes your symptoms. Available at Ahmad Medico, Pakistan’s premier online pharmacy, this prescription biologic contains omalizumab, an anti-IgE antibody that works differently from steroids or antihistamines. Below, you’ll find complete information on how Xolair injection works, who needs it, its side effects, and its price in Pakistan, based on approved clinical data.
What Is Xolair 150mg Injection?
Xolair injection contains omalizumab, a humanised monoclonal antibody made through recombinant DNA technology. Each pre-filled syringe holds 150mg of omalizumab in a 1ml solution, ready for a subcutaneous injection. Unlike inhaled or oral treatments, Xolair targets immunoglobulin E (IgE), the antibody responsible for triggering allergic reactions. By binding to free IgE, it stops IgE from attaching to receptors on mast cells and basophils, the cells that release histamine and other chemicals during an allergic reaction. Your doctor prescribes Xolair as an add-on therapy, not a standalone treatment for sudden attacks.
What Is Xolair 150mg Injection Used For?
Doctors prescribe Xolair 150mg injection for several IgE-mediated allergic conditions that don’t respond well to standard medicines. The main uses of Xolair injection include:
- Allergic asthma – for adults, adolescents, and children above 6 years with severe persistent allergic asthma, confirmed through a positive skin or blood test for an airborne allergen, whose symptoms continue despite high-dose inhaled corticosteroids and a long-acting beta2-agonist
- Chronic urticaria (chronic spontaneous urticaria) – for patients 12 years and above whose hives and itching persist even after regular antihistamine treatment
- Chronic rhinosinusitis with nasal polyps – for adults with severe nasal polyps who don’t get adequate relief from intranasal corticosteroids
Your pulmonologist, allergist, or dermatologist decides which condition qualifies you for Xolair therapy after checking your IgE levels, body weight, and treatment history.
How Xolair Injection Works
Xolair injection works by reducing the amount of free IgE circulating in your blood. Once IgE levels drop, fewer allergic triggers reach the receptors on mast cells and basophils, and your body releases less histamine and fewer inflammatory chemicals. This anti-IgE antibody mechanism explains why Xolair takes time to show results: most patients notice measurable improvement in asthma control between 12 and 16 weeks of regular dosing, while urticaria symptoms often ease within the first few weeks.
How Is Xolair 150mg Injection Given?
Xolair is a subcutaneous injection, meaning it goes into the fatty layer just under the skin, usually in the thigh, abdomen, or upper arm. A doctor or trained healthcare provider gives your first three doses, since the risk of an allergic reaction to the injection itself is highest during this period. After that, if you have no history of anaphylaxis, your doctor may train you or a caregiver to give the injection at home.
Your dose and dosing frequency depend on:
- Your baseline serum IgE level, tested before treatment begins
- Your body weight
- The condition being treated (allergic asthma and nasal polyps use weight-and-IgE-based dosing; chronic urticaria uses a fixed 300mg dose, split into two 150mg injections, every four weeks)
Only your prescribing doctor can confirm the correct dose for your case, since an incorrect dose reduces effectiveness or raises the chance of side effects.
What Are the Side Effects of Xolair 150mg Injection?
Like every biologic medicine, Xolair side effects range from mild to serious. Most people tolerate the injection well, but you should still know what to watch for.
Common side effects include:
- Injection site reactions such as pain, redness, swelling, or itching
- Headache
- Fever, more common in children
- Upper abdominal pain
- Joint pain
Less common but serious reactions include:
- Anaphylaxis or other severe allergic reactions, mostly within the first three doses
- Serum sickness, with joint pain, rash, fever, and swollen glands appearing days after an injection
- Churg-Strauss syndrome or systemic eosinophilia, usually linked to reducing oral steroids too quickly
- A drop in platelet count
Because most severe reactions surface soon after an injection, your healthcare provider monitors you for a period after each of your first three doses. Report facial or throat swelling, breathing difficulty, dizziness, or a spreading rash immediately, since these signal an emergency.
Who Should Avoid Xolair Injection?
Xolair isn’t suitable for everyone. Your doctor avoids prescribing it, or takes extra precaution, in the following situations:
- Active asthma attacks, acute bronchospasm, or status asthmaticus, since Xolair treats long-term inflammation, not sudden flare-ups
- A known hypersensitivity to omalizumab or any excipient in the injection
- Pregnancy or breastfeeding, where the medicine is used only if clearly needed and under close supervision
- Autoimmune disease, immune complex-related conditions, or existing kidney or liver impairment
- A high risk of parasitic (helminth) infection, particularly before travelling to an endemic region
- Known latex sensitivity, since the syringe’s needle cap contains a natural rubber derivative
Tell your doctor about every other medicine, corticosteroid dose, or health condition you have before starting Xolair, so they can adjust your plan safely.
How Much Does Xolair 150mg Injection Cost in Pakistan?
The Xolair injection price in Pakistan generally falls between Rs. 35,000 and Rs. 55,000 per 150mg pre-filled syringe, though the exact figure moves with currency rates, import batches, and supplier stock. Since asthma and nasal polyp dosing often needs more than one syringe per session, your total cost depends on your prescribed dose, not just a single unit price. For an accurate Xolair 150 mg injection price quote in Pakistan based on your prescription, reach out to our pharmacist team at Ahmad Medico before you order, so you know your full treatment cost upfront.
Why Order Xolair 150mg Injection From Ahmad Medico?
Ahmad Medico sources every Xolair injection directly from licensed distributors, so you receive a genuine, correctly stored product every time. Since Xolair needs refrigeration between 2°C and 8°C, we pack every order in temperature-controlled conditions and ship it across Pakistan with cold-chain handling intact. Our pharmacist team checks your prescription before dispatch and stays available to answer questions about your dose, storage at home, or any reaction you notice after an injection.
Frequently Asked Questions
What is Xolair 150mg injection used for?
Xolair 150mg injection treats severe persistent allergic asthma, chronic spontaneous urticaria, and chronic rhinosinusitis with nasal polyps in patients whose IgE-mediated symptoms don’t respond to standard treatment.
What are the side effects of Xolair 150mg injection?
The most common side effects are injection site reactions, headache, fever, and joint pain. Serious but less common effects include anaphylaxis, serum sickness, and a drop in platelet count, which need prompt medical attention.
How much does Xolair 150mg injection cost in Pakistan?
The price generally ranges from Rs. 45,000 to Rs. 55,000 per 150mg syringe, depending on your supplier and how many syringes your dose requires. Contact Ahmad Medico for a quote based on your prescription.
Can I inject Xolair myself at home?
Only after your first three doses, and only if your doctor confirms you have no history of anaphylaxis. You or a caregiver must first learn the correct injection technique from your healthcare provider.
How long does Xolair take to work?
Most asthma patients see meaningful improvement between 12 and 16 weeks. Chronic urticaria symptoms often start easing within a few weeks of the first dose.
Is Xolair injection safe during pregnancy?
Available pregnancy registry data show no clear increase in birth defects, but your doctor prescribes Xolair during pregnancy only if the benefit clearly outweighs the risk.
